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human IQSEC2 shRNA silencing Adenovirus

Name 
Ad-h-IQSEC2-shRNA
Cat No 
shADV-212383
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human IQSEC2.

shADV-212383
Ad-h-IQSEC2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human IQSEC2 (IQ motif and Sec7 domain 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
BRAG1; MRX1; MRX18; MRX78
Description (Vector)
IQSEC2 encodes a guanine nucleotide exchange factor for the ARF family of small GTP-binding proteins. The encoded protein is a component of the postsynaptic density at excitatory synapses, and may play a critical role in cytoskeletal and synaptic organization through the activation of selected ARF substrates including ARF1 and ARF6. Mutations in this gene have been implicated in nonsyndromic X-linked mental retardation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Gene ID
23096
Gene Name (Vector)
IQ motif and Sec7 domain 2
Gene Symbol
IQSEC2
HGNC ID
HGNC:29059
ORF Size (aa)
2850
ORF Size (bp)
2850 bp
RefSeq ID
NM_015075
RefSeq Synonyms
NM_015075, NM_001243197, NM_001111125, BC156683,
Species
human
UniGene ID
Hs.496138

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.