human ICAM2 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human ICAM2.
shADV-211748
Ad-h-ICAM2-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human ICAM2 (intercellular adhesion molecule 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CD antigen CD102; CD102; ICAM-2; intercellular adhesion molecule 2
Description (eCommerce)
ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM-2 may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P13598].
Description (Vector)
ICAM2 is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. Several transcript variants encoding the same protein have been found for this gene.
Gene ID
3384
Gene Name (eCommerce)
intercellular adhesion molecule 2
Gene Name (Vector)
intercellular adhesion molecule 2
Gene Symbol
ICAM2
HGNC ID
HGNC:5345
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
828
ORF Size (bp)
828 bp
Protein Name (eCommerce)
Intercellular adhesion molecule 2
RefSeq ID
NM_000873
RefSeq Synonyms
NM_001099789, NM_001099788, NM_001099787, NM_001099786, NM_000873, BC003097,
Research Areas
Immunology,Signal Transduction
Research Areas (Faceted)
signal_transduction,immunology
Species
human
Target Sentence
ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM-2 may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P13598].
UniGene ID
Hs.431460
UniProt ID (eCommerce)
P13598
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.