human HSPD1 shRNA silencing Adenovirus

Name 
Ad-h-HSPD1-shRNA
Cat No 
shADV-211671
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human HSPD1.

shADV-211671
Ad-h-HSPD1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human HSPD1 (heat shock protein family D (Hsp60) member 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
60 kDa chaperonin; 60 kDa heat shock protein, mitochondrial; chaperonin 60; CPN60; epididymis secretory sperm binding protein; GROEL; heat shock 60kDa protein 1 (chaperonin); Heat shock protein 60; heat shock protein 65; HLD4; HSP60; HSP-60; HSP65; HuCHA60; mitochondrial matrix protein P1; P60 lymphocyte protein; short heat shock protein 60 Hsp60s1; SPG13
Description (eCommerce)
Heat shock protein 60 (HSP60) is a member of the chaperonin family. HSP60 is a mitochondrial protein that may function as a signaling molecule in the innate immune system. It is essential for the folding and assembly of newly imported proteins in the mitochondria. [taken from NCBI Entrez Gene (GeneID: 3329)].
Description (Vector)
HSPD1 encodes a member of the chaperonin family. The encoded mitochondrial protein may function as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly imported proteins in the mitochondria. HSPD1 is adjacent to a related family member and the region between the 2 genes functions as a bidirectional promoter. Several pseudogenes have been associated with this gene. Two transcript variants encoding the same protein have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 13.
Gene ID
3329
Gene Name (eCommerce)
heat shock protein family D (Hsp60) member 1
Gene Name (Vector)
heat shock protein family D (Hsp60) member 1
Gene Symbol
HSPD1
HGNC ID
HGNC:5261
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1722
ORF Size (bp)
1722 bp
Protein Name (eCommerce)
60 kDa heat shock protein, mitochondrial
RefSeq ID
NM_002156
RefSeq Synonyms
NM_199440, NM_002156, BC073746, BC067082, BC003030, BC002676,
Research Areas
Apoptosis,DNA Replication,Host-Virus Interactions,Immunology,Mitochondrion,Neurobiology,Neurodegeneration,Protein Folding,Signal Transduction,Toll-like Receptor Signaling
Research Areas (Faceted)
cell_biology,genetics,immunology,infectious_disease,neurobiology,signal_transduction,transcription_translation
Species
human
Target Sentence
Heat shock protein 60 (HSP60) is a member of the chaperonin family. HSP60 is a mitochondrial protein that may function as a signaling molecule in the innate immune system. It is essential for the folding and assembly of newly imported proteins in the mitochondria. [taken from NCBI Entrez Gene (GeneID: 3329)].
UniGene ID
Hs.632539
UniProt ID (eCommerce)
P10809

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.