human HSPB8 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human HSPB8.
shADV-211660
Ad-h-HSPB8-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human HSPB8 (heat shock protein family B (small) member 8). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CMT2L; DHMN2; E2IG1; H11; HMN2; HMN2A; HSP22
Description (Vector)
HSPB8 belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.
Gene ID
26353
Gene Name (Vector)
heat shock protein family B (small) member 8
Gene Symbol
HSPB8
HGNC ID
HGNC:30171
ORF Size (aa)
591
RefSeq ID
NM_014365
RefSeq Synonyms
NM_014365, BC002673,
Species
human
UniGene ID
Hs.400095
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.