human LCAT Over-expression AAV

Name 
AAV-h-LCAT
Cat No 
AAV-213724
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human LCAT.

AAV-213724
AAV-h-LCAT

Ready-to-use AAV expressing Human LCAT (lecithin-cholesterol acyltransferase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Description (Vector)
LCAT encodes the extracellular cholesterol esterifying enzyme, lecithin-cholesterol acyltransferase. The esterification of cholesterol is required for cholesterol transport. Mutations in this gene have been found to cause fish-eye disease as well as LCAT deficiency.
Gene ID
3931
Gene Name (Vector)
lecithin-cholesterol acyltransferase
Gene Symbol
LCAT
HGNC ID
HGNC:6522
ORF Size (aa)
1323
ORF Size (bp)
1323 bp
RefSeq ID
NM_000229
RefSeq Synonyms
NM_000229, BC014781,
Species
human
UniGene ID
Hs.387239

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.