human HP1BP3 shRNA silencing Adenovirus

Name 
Ad-h-HP1BP3-shRNA
Cat No 
shADV-211491
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human HP1BP3.

shADV-211491
Ad-h-HP1BP3-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human HP1BP3 (heterochromatin protein 1 binding protein 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
heterochromatin protein 1-binding protein 3; HP1BP74; HP1-BP74; Protein HP1-BP74
Description (eCommerce)
HP1BP3 is a component of heterochromatin that maintains heterochromatin integrity during G1/S progression and regulates the duration of G1 phase to critically influence cell proliferative capacity. Mediates chromatin condensation during hypoxia, leading to increased tumor cell viability, radio-resistance, chemo-resistance and self-renewal. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q5SSJ5].
Gene ID
50809
Gene Name (eCommerce)
heterochromatin protein 1 binding protein 3
Gene Name (Vector)
heterochromatin protein 1 binding protein 3
Gene Symbol
HP1BP3
HGNC ID
HGNC:24973
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1206
ORF Size (bp)
1206 bp
Protein Name (eCommerce)
Heterochromatin protein 1-binding protein 3
RefSeq ID
NM_016287
RefSeq Synonyms
NM_016287, BC046170, BC045660, BC032139,
Research Areas
Cell Biology,Translational Control
Research Areas (Faceted)
cell_biology,transcription_translation
Species
human
Target Sentence
HP1BP3 is a component of heterochromatin that maintains heterochromatin integrity during G1/S progression and regulates the duration of G1 phase to critically influence cell proliferative capacity. Mediates chromatin condensation during hypoxia, leading to increased tumor cell viability, radio-resistance, chemo-resistance and self-renewal. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q5SSJ5].
UniGene ID
Hs.142442
UniProt ID (eCommerce)
Q5SSJ5

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.