human HMOX2 shRNA silencing Adenovirus

Name 
Ad-h-HMOX2-shRNA
Cat No 
shADV-211315
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human HMOX2.

shADV-211315
Ad-h-HMOX2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human HMOX2 (heme oxygenase 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
heme oxygenase (decycling) 2; heme oxygenase 2; HO-2
Description (eCommerce)
Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances [taken from NCBI Entrez Gene (Gene ID: 3163)].
Description (Vector)
Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 isozymes, an inducible heme oxygenase-1 and a constitutive heme oxygenase-2. HMOX1 and HMOX2 belong to the heme oxygenase family. Alternative splice variants encoding the same protein have been identified at this locus.
Gene ID
3163
Gene Name (eCommerce)
heme oxygenase 2
Gene Name (Vector)
heme oxygenase 2
Gene Symbol
HMOX2
HGNC ID
HGNC:5014
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
951
ORF Size (bp)
951 bp
Protein Name (eCommerce)
Heme oxygenase 2
RefSeq ID
NM_002134
RefSeq Synonyms
NM_002134, NM_001286271, NM_001286270, NM_001286269, NM_001286268, NM_001286267, NM_001127206, NM_001127205, NM_001127204, BC002396,
Research Areas
Hypoxia,Metabolism/Metabolic Process
Research Areas (Faceted)
cell_biology,metabolism
Species
human
Target Sentence
Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances [taken from NCBI Entrez Gene (Gene ID: 3163)].
UniGene ID
Hs.284279
UniProt ID (eCommerce)
P30519

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.