human LARP7 Over-expression AAV

Name 
AAV-h-LARP7
Cat No 
AAV-213685
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human LARP7.

AAV-213685
AAV-h-LARP7

Ready-to-use AAV expressing Human LARP7 (La ribonucleoprotein domain family member 7). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ALAZS; HDCMA18P; La ribonucleoprotein domain family member 7; la-related protein 7; PIP7S; P-TEFb-interaction protein for 7SK stabilitY
Description (eCommerce)
La-related protein 7 (LARP7) is a component of 7SK ribonucleoprotein (RNP). The 7SK snRNP plays a role in regulating the activity of the positive transcription elongation factor b (P-TEFb) complex.
Description (Vector)
LARP7 encodes a protein which is found in the 7SK snRNP (small nuclear ribonucleoprotein). This snRNP complex inhibits a cyclin-dependent kinase, positive transcription elongation factor b, which is required for paused RNA polymerase II at a promoter to begin transcription elongation. A pseudogene of this gene is located on chromosome 3. Alternative splicing results in multiple transcript variants.
Gene ID
51574
Gene Name (eCommerce)
La ribonucleoprotein domain family member 7
Gene Name (Vector)
La ribonucleoprotein domain family member 7
Gene Symbol
LARP7
HGNC ID
HGNC:24912
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1749
ORF Size (bp)
1749 bp
Protein Name (eCommerce)
La-related protein 7
RefSeq ID
NM_016648
RefSeq Synonyms
NM_016648, NM_015454, NM_001267039, BC066945,
Research Areas
Neurobiology,RNA Binding,RNA Processing,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,genetics,neurobiology,transcription_translation
Species
human
Target Sentence
La-related protein 7 (LARP7) is a component of 7SK ribonucleoprotein (RNP). The 7SK snRNP plays a role in regulating the activity of the positive transcription elongation factor b (P-TEFb) complex.
UniGene ID
Hs.713663
UniProt ID (eCommerce)
Q4G0J3

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.