human HAUS3 shRNA silencing Adenovirus

Name
Ad-h-HAUS3-shRNA

Cat No
shADV-210798

Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human HAUS3.

shADV-210798

Ad-h-HAUS3-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human HAUS3 (HAUS augmin like complex subunit 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Validated

No

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

C4orf15; dgt3; HAUS augmin-like complex subunit 3; IT1

Description (eCommerce)

HAUS3 is a component of the HAUS augmin-like protein complex, which plays a key role in cytokinesis and mitosis. Disruption of HAUS3 causes mitotic defects resulting from fragmentation of centrosomes and microtubule destabilizatio [taken from NCBI Entrez Gene (Gene ID: 79441)].

Description (Vector)

HAUS3 is 1 of 8 subunits of the 390-kD human augmin complex, or HAUS complex. The augmin complex was first identified in Drosophila, and its name comes from the Latin verb 'augmentare,' meaning 'to increase.' The augmin complex is a microtubule-binding complex involved in microtubule generation within the mitotic spindle and is vital to mitotic spindle assembly (Goshima et al., 2008 (PubMed 18443220); Uehara et al., 2009 (PubMed 19369198)).(supplied by OMIM, Nov 2010)

Gene ID

79441

Gene Name (eCommerce)

HAUS augmin like complex subunit 3

Gene Name (Vector)

HAUS augmin like complex subunit 3

Gene Symbol

HAUS3

HGNC ID

HGNC:28719

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

1437

ORF Size (bp)

1437 bp

Protein Name (eCommerce)

HAUS augmin-like complex subunit 3

RefSeq ID

NM_024511

RefSeq Synonyms

NM_024511, NM_001303143, BC025356, BC003648,

Research Areas

Cell Cycle,Cell Division,Cytoskeleton

Research Areas (Faceted)

cell_biology,cell_cycle,genetics

Species

human

Target Sentence

HAUS3 is a component of the HAUS augmin-like protein complex, which plays a key role in cytokinesis and mitosis. Disruption of HAUS3 causes mitotic defects resulting from fragmentation of centrosomes and microtubule destabilizatio [taken from NCBI Entrez Gene (Gene ID: 79441)].

UniGene ID

Hs.665869

UniProt ID (eCommerce)

Q68CZ6

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.