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human HAND2 shRNA silencing Adenovirus

Name 
Ad-h-HAND2-shRNA
Cat No 
shADV-210774
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human HAND2.

shADV-210774
Ad-h-HAND2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human HAND2 (heart and neural crest derivatives expressed 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
bHLHa26; dHand; DHAND2; Hed; Thing2
Description (Vector)
HAND2 belongs to the basic helix-loop-helix family of transcription factors. This gene product is one of two closely related family members, the HAND proteins, which are asymmetrically expressed in the developing ventricular chambers and play an essential role in cardiac morphogenesis. Working in a complementary fashion, they function in the formation of the right ventricle and aortic arch arteries, implicating them as mediators of congenital heart disease. In addition, this transcription factor plays an important role in limb and branchial arch development.
Gene ID
9464
Gene Name (Vector)
heart and neural crest derivatives expressed 2
Gene Symbol
HAND2
HGNC ID
HGNC:4808
ORF Size (aa)
543
RefSeq ID
NM_021973
RefSeq Synonyms
NM_021973, BC101406,
Species
human
UniGene ID
Hs.388245

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.