human H1F0 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human H1F0.
shADV-210722
Ad-h-H1F0-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human H1F0 (H1 histone family member 0). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
H1.0, H1(0), H1-0; H10; H1FV; histone H1'; histone H1(0); histone H1.0
Description (eCommerce)
Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures. The H1F0 histones are found in cells that are in terminal stages of differentiation or that have low rates of cell division [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P07305].
Description (Vector)
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H1 family.
Gene ID
3005
Gene Name (eCommerce)
H1 histone family member 0
Gene Name (Vector)
H1 histone family member 0
Gene Symbol
H1F0
HGNC ID
HGNC:4714
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
585
Protein Name (eCommerce)
Histone H1.0
RefSeq ID
NM_005318
RefSeq Synonyms
NM_005318, BC029046, BC000145,
Research Areas
Apoptosis,Golgi Apparatus
Research Areas (Faceted)
cell_biology
Species
human
Target Sentence
Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures. The H1F0 histones are found in cells that are in terminal stages of differentiation or that have low rates of cell division [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P07305].
UniGene ID
Hs.715673
UniProt ID (eCommerce)
P07305
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.