human GRIN1 shRNA silencing Adenovirus

Name 
Ad-h-GRIN1-shRNA
Cat No 
shADV-210521
Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human GRIN1.

shADV-210521
Ad-h-GRIN1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human GRIN1 (glutamate ionotropic receptor NMDA type subunit 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
GluN1; MRD8; NMD-R1; NMDA1; NMDAR1; NR1
Description (Vector)
GRIN1 is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described.
Gene ID
2902
Gene Name (Vector)
glutamate ionotropic receptor NMDA type subunit 1
Gene Symbol
GRIN1
HGNC ID
HGNC:4584
ORF Size (aa)
2814
ORF Size (bp)
2814 bp
RefSeq ID
NM_000832
RefSeq Synonyms
NM_021569, NM_007327, NM_001185091, NM_001185090, NM_000832, BC156961, BC156097,
Species
human
UniGene ID
Hs.558334

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.