human GGCX shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human GGCX.
shADV-209844
Ad-h-GGCX-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human GGCX (gamma-glutamyl carboxylase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
VKCFD1
Description (Vector)
GGCX encodes an enzyme which catalyzes the posttranslational modification of vitamin K-dependent protein. Many of these vitamin K-dependent proteins are involved in coagulation so the function of the encoded enzyme is essential for hemostasis. Mutations in this gene are associated with vitamin K-dependent coagulation defect and PXE-like disorder with multiple coagulation factor deficiency. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene ID
2677
Gene Name (Vector)
gamma-glutamyl carboxylase
Gene Symbol
GGCX
HGNC ID
HGNC:4247
ORF Size (aa)
2277
ORF Size (bp)
2277 bp
RefSeq ID
NM_000821
RefSeq Synonyms
NM_001311312, NM_001142269, NM_000821, BC013979,
Species
human
UniGene ID
Hs.77719
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.