Promotional banner reading 'FALL SAVINGS' with expiry date August 31 on an orange background; features a group of people with orange stacked blocks on the right and discounts for services and catalog products.

human GGA1 shRNA silencing Adenovirus

Name 
Ad-h-GGA1-shRNA
Cat No 
shADV-209837
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human GGA1.

shADV-209837
Ad-h-GGA1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human GGA1 (golgi associated, gamma adaptin ear containing, ARF binding protein 1). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
ADP-ribosylation factor binding protein 1; ADP-ribosylation factor-binding protein GGA1; gamma-adaptin related protein 1; Gamma-adaptin-related protein 1; golgi-localized, gamma ear-containing, ARF-binding protein 1
Description (eCommerce)
Gamma-adaptin-related protein 1 (GGA1) is a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) protein family. Members of this family are ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins [taken from NCBI Entrez Gene (Gene ID: 26088)].
Description (Vector)
GGA1 encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) protein family. Members of this family are ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene ID
26088
Gene Name (eCommerce)
golgi associated, gamma adaptin ear containing, ARF binding protein 1
Gene Name (Vector)
golgi associated, gamma adaptin ear containing, ARF binding protein 1
Gene Symbol
GGA1
HGNC ID
HGNC:17842
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1659
ORF Size (bp)
1659 bp
Protein Name (eCommerce)
ADP-ribosylation factor-binding protein GGA1
RefSeq ID
NM_001001560
RefSeq Synonyms
NM_013365, NM_001172688, NM_001172687, NM_001001561, NM_001001560, BC044629,
Research Areas
Golgi Apparatus,Lysosome
Research Areas (Faceted)
cell_biology
Species
human
Target Sentence
Gamma-adaptin-related protein 1 (GGA1) is a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) protein family. Members of this family are ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins [taken from NCBI Entrez Gene (Gene ID: 26088)].
UniGene ID
Hs.499158
UniProt ID (eCommerce)
Q9UJY5

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.