human FMO4 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human FMO4.
shADV-209183
Ad-h-FMO4-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human FMO4 (flavin containing monooxygenase 4). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
FMO2
Description (Vector)
Metabolic N-oxidation of the diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in man resulting in a small subpopulation with reduced TMA N-oxidation capacity resulting in fish odor syndrome Trimethylaminuria. Three forms of the enzyme, FMO1 found in fetal liver, FMO2 found in adult liver, and FMO3 are encoded by genes clustered in the 1q23-q25 region. Flavin-containing monooxygenases are NADPH-dependent flavoenzymes that catalyzes the oxidation of soft nucleophilic heteroatom centers in drugs, pesticides, and xenobiotics.
Gene ID
2329
Gene Name (Vector)
flavin containing monooxygenase 4
Gene Symbol
FMO4
HGNC ID
HGNC:3772
ORF Size (aa)
1677
ORF Size (bp)
1677 bp
RefSeq ID
NM_002022
RefSeq Synonyms
NM_002022, BC002780,
Species
human
UniGene ID
Hs.386502
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.