human FKTN shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human FKTN.
shADV-209075
Ad-h-FKTN-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human FKTN (fukutin). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CMD1X; FCMD; LGMD2M; MDDGA4; MDDGB4; MDDGC4
Description (Vector)
FKTN is a putative transmembrane protein that is localized to the cis-Golgi compartment, where it may be involved in the glycosylation of alpha-dystroglycan in skeletal muscle. The encoded protein is thought to be a glycosyltransferase and could play a role in brain development. Defects in this gene are a cause of Fukuyama-type congenital muscular dystrophy (FCMD), Walker-Warburg syndrome (WWS), limb-girdle muscular dystrophy type 2M (LGMD2M), and dilated cardiomyopathy type 1X (CMD1X). Alternatively spliced transcript variants have been found for this gene.
Gene ID
2218
Gene Name (Vector)
fukutin
Gene Symbol
FKTN
HGNC ID
HGNC:3622
ORF Size (aa)
1386
ORF Size (bp)
1386 bp
RefSeq ID
NM_006731
RefSeq Synonyms
NM_006731, NM_001198963, NM_001079802, BC117700, BC117699, BC112038, BC101808,
Species
human
UniGene ID
Hs.55777
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.