human FGFRL1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human FGFRL1.
shADV-208998
Ad-h-FGFRL1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human FGFRL1 (fibroblast growth factor receptor-like 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
FGFR5; FHFR
Description (Vector)
FGFRL1 is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. A marked difference between this gene product and the other family members is its lack of a cytoplasmic tyrosine kinase domain. The result is a transmembrane receptor that could interact with other family members and potentially inhibit signaling. Multiple alternatively spliced transcript variants encoding the same isoform have been found for this gene.
Gene ID
53834
Gene Name (Vector)
fibroblast growth factor receptor-like 1
Gene Symbol
FGFRL1
HGNC ID
HGNC:3693
ORF Size (aa)
1515
ORF Size (bp)
1515 bp
RefSeq ID
NM_001004356
RefSeq Synonyms
NM_021923, NM_001004358, NM_001004356, BC036769, BC013955,
Species
human
UniGene ID
Hs.193326
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.