human KRT86 Over-expression AAV

Name 
AAV-h-KRT86
Cat No 
AAV-213468
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human KRT86.

AAV-213468
AAV-h-KRT86

Ready-to-use AAV expressing Human KRT86 (keratin 86). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
FLJ25176; Hb1; HB6; hHb6; KRTHB1; KRTHB6; MNX;
Description (Vector)
KRT86 is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this hair keratin, as well as KRTHB1 and KRTHB3, is found primarily in the hair cortex. Mutations in this gene and KRTHB1 have been observed in patients with a rare dominant hair disease, monilethrix.
Gene ID
3892
Gene Name (Vector)
keratin 86
Gene Symbol
KRT86
HGNC ID
HGNC:6463
ORF Size (aa)
1461
ORF Size (bp)
1461 bp
RefSeq ID
NM_002284
RefSeq Synonyms
NM_002284, NM_001320198, BC069585,
Species
human
UniGene ID
Hs.278658

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.