human EPHA3 shRNA silencing Adenovirus

Name 
Ad-h-EPHA3-shRNA
Cat No 
shADV-207980
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human EPHA3.

shADV-207980
Ad-h-EPHA3-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human EPHA3 (EPH receptor A3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
EK4; ETK; ETK1; HEK; HEK4; TYRO4
Description (Vector)
EPHA3 belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. EPHA3 encodes a protein that binds ephrin-A ligands. Two alternatively spliced transcript variants have been described for this gene.
Gene ID
2042
Gene Name (Vector)
EPH receptor A3
Gene Symbol
EPHA3
HGNC ID
HGNC:3387
ORF Size (aa)
2952
ORF Size (bp)
2952 bp
RefSeq ID
NM_005233
RefSeq Synonyms
NM_182644, NM_005233, BC063282,
Species
human
UniGene ID
Hs.123642

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.