human ENPP1 shRNA silencing Adenovirus

Name 
Ad-h-ENPP1-shRNA
Cat No 
shADV-207929
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human ENPP1.

shADV-207929
Ad-h-ENPP1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human ENPP1 (ectonucleotide pyrophosphatase/phosphodiesterase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
ARHR2; COLED; M6S1; NPP1; NPPS; PC-1; PCA1; PDNP1
Description (Vector)
ENPP1 is a member of the ecto-nucleotide pyrophosphatase/phosphodiesterase (ENPP) family. The encoded protein is a type II transmembrane glycoprotein comprising two identical disulfide-bonded subunits. This protein has broad specificity and cleaves a variety of substrates, including phosphodiester bonds of nucleotides and nucleotide sugars and pyrophosphate bonds of nucleotides and nucleotide sugars. This protein may function to hydrolyze nucleoside 5' triphosphates to their corresponding monophosphates and may also hydrolyze diadenosine polyphosphates. Mutations in this gene have been associated with 'idiopathic' infantile arterial calcification, ossification of the posterior longitudinal ligament of the spine (OPLL), and insulin resistance.
Gene ID
5167
Gene Name (Vector)
ectonucleotide pyrophosphatase/phosphodiesterase 1
Gene Symbol
ENPP1
HGNC ID
HGNC:3356
ORF Size (aa)
2622
ORF Size (bp)
2622 bp
RefSeq ID
NM_006208
RefSeq Synonyms
NM_006208, BC059375,
Species
human
UniGene ID
Hs.527295

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.