mouse ENPP1 shRNA silencing Adenovirus

Name 
Ad-m-ENPP1-shRNA
Cat No 
shADV-258385
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Enpp1.

shADV-258385
Ad-m-ENPP1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Enpp1 (ectonucleotide pyrophosphatase/phosphodiesterase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
4833416E15Rik; AI428932; C76301; CD203c; E-NPP 1; E-NPP1; Ly-41; M6S1; NPP1; Npps; PC-1; Pca; Pca-1; Pdnp1; ttw; twy
Description (Vector)
Involved primarily in ATP hydrolysis at the plasma membrane. Plays a role in regulating pyrophosphate levels, and functions in bone mineralization and soft tissue calcification. In vitro, has a broad specificity, hydrolyzing other nucleoside 5' triphosphates such as GTP, CTP, TTP and UTP to their corresponding monophosphates with release of pyrophosphate and diadenosine polyphosphates, and also 3',5'-cAMP to AMP. May also be involved in the regulation of the availability of nucleotide sugars in the endoplasmic reticulum and Golgi, and the regulation of purinergic signaling. Appears to modulate insulin sensitivity.
Gene ID
18605
Gene Name (Vector)
ectonucleotide pyrophosphatase/phosphodiesterase 1
Gene Symbol
Enpp1
ORF Size (aa)
2718
ORF Size (bp)
2718 bp
RefSeq ID
NM_008813
RefSeq Synonyms
NM_008813, NM_001308329, NM_001308327, BC160371,
Species
mouse
UniGene ID
Mm.477765

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.