human ELP4 shRNA silencing Adenovirus

Name 
Ad-h-ELP4-shRNA
Cat No 
shADV-207867
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human ELP4.

shADV-207867
Ad-h-ELP4-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human ELP4 (elongator acetyltransferase complex subunit 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
AN; AN2; C11orf19; dJ68P15A.1; elongation protein 4 homolog; elongator complex protein 4; hELP4; PAX6 neighbor gene protein; PAX6NEB; PAXNEB
Description (eCommerce)
Elongation protein 4 homolog (ELP4) is a component of the six subunit elongator complex, a histone acetyltransferase complex that associates directly with RNA polymerase II during transcriptional elongation [taken from NCBI Entrez Gene (Gene ID: 26610)].
Description (Vector)
ELP4 encodes a component of the six subunit elongator complex, a histone acetyltransferase complex that associates directly with RNA polymerase II during transcriptional elongation. The human gene can partially complement sensitivity phenotypes of yeast ELP4 deletion mutants. Alternatively spliced variants that encode different protein isoforms have been described but the full-length nature of only one has been determined.
Gene ID
26610
Gene Name (eCommerce)
elongator acetyltransferase complex subunit 4
Gene Name (Vector)
elongator acetyltransferase complex subunit 4
Gene Symbol
ELP4
HGNC ID
HGNC:1171
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1608
ORF Size (bp)
1608 bp
Protein Name (eCommerce)
Elongator complex protein 4
RefSeq ID
NM_019040
RefSeq Synonyms
NM_019040, NM_001288726, NM_001288725, BC012514,
Research Areas
Chromatin Remodeling,Histone Modification,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,genetics,transcription_translation
Species
human
Target Sentence
Elongation protein 4 homolog (ELP4) is a component of the six subunit elongator complex, a histone acetyltransferase complex that associates directly with RNA polymerase II during transcriptional elongation [taken from NCBI Entrez Gene (Gene ID: 26610)].
UniGene ID
Hs.175534
UniProt ID (eCommerce)
Q96EB1

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.