human ELL shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human ELL.
shADV-207843
Ad-h-ELL-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human ELL (elongation factor for RNA polymerase II). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
C19orf17; eleven-nineteen lysine-rich leukemia protein; ELL gene (11-19 lysine-rich leukemia gene); ELL1; elongation factor RNA polymerase II; MEN; PPP1R68; protein phosphatase 1, regulatory subunit 68; RNA polymerase II elongation factor ELL
Description (eCommerce)
Eleven-nineteen lysine-rich leukemia protein (ELL) was originally identified in a screen for genes that fuse to MLL (myeloid-lymphoid leukemia) in the t(11;19)(q23;p13.1) breakpoint. ELL is an elongation factor that increases the catalytic rate of RNA pol II by suppressing transient pausing of RNA pol II. ELL has been shown to be essential to development and important to cell growth and survival.
Gene ID
8178
Gene Name (eCommerce)
elongation factor for RNA polymerase II
Gene Name (Vector)
elongation factor for RNA polymerase II
Gene Symbol
ELL
HGNC ID
HGNC:23114
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1866
ORF Size (bp)
1866 bp
Protein Name (eCommerce)
RNA polymerase II elongation factor ELL
RefSeq ID
NM_006532
RefSeq Synonyms
NM_006532, BC064558, BC049195,
Research Areas
Cancer,Gene Expression,Host-Virus Interactions,Kinase/Phosphatase,Transcription Factor/Regulator
Research Areas (Faceted)
cancer,cell_biology,infectious_disease,signal_transduction,transcription_translation
Species
human
Target Sentence
Eleven-nineteen lysine-rich leukemia protein (ELL) was originally identified in a screen for genes that fuse to MLL (myeloid-lymphoid leukemia) in the t(11;19)(q23;p13.1) breakpoint. ELL is an elongation factor that increases the catalytic rate of RNA pol II by suppressing transient pausing of RNA pol II. ELL has been shown to be essential to development and important to cell growth and survival.
UniGene ID
Hs.515260
UniProt ID (eCommerce)
P55199
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.