human DSG1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human DSG1.
shADV-207350
Ad-h-DSG1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human DSG1 (desmoglein 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CDHF4; DG1; DSG; EPKHE; EPKHIA; PPKS1; SPPK1
Description (Vector)
Desmosomes are cell-cell junctions between epithelial, myocardial and certain other cell types. Desmoglein 1 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. The protein encoded by this gene has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus foliaceus.
Gene ID
1828
Gene Name (Vector)
desmoglein 1
Gene Symbol
DSG1
HGNC ID
HGNC:3048
ORF Size (aa)
3147
ORF Size (bp)
3147 bp
RefSeq ID
NM_001942
RefSeq Synonyms
NM_001942, BC153001, BC148374,
Species
human
UniGene ID
Hs.2633
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.