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human DSG1 Over-expression AAV

Name 
AAV-h-DSG1
Cat No 
AAV-207350
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human DSG1.

AAV-207350
AAV-h-DSG1

Ready-to-use AAV expressing Human DSG1 (desmoglein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CDHF4; DG1; DSG; EPKHE; EPKHIA; PPKS1; SPPK1
Description (Vector)
Desmosomes are cell-cell junctions between epithelial, myocardial and certain other cell types. Desmoglein 1 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. The protein encoded by this gene has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus foliaceus.
Gene ID
1828
Gene Name (Vector)
desmoglein 1
Gene Symbol
DSG1
HGNC ID
HGNC:3048
ORF Size (aa)
3147
ORF Size (bp)
3147 bp
RefSeq ID
NM_001942
RefSeq Synonyms
NM_001942, BC153001, BC148374,
Species
human
UniGene ID
Hs.2633

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.