human DOC2B shRNA silencing Adenovirus

Name
Ad-h-DOC2B-shRNA

Cat No
shADV-207222

Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human DOC2B.

shADV-207222

Ad-h-DOC2B-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human DOC2B (double C2 domain beta). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Validated

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

DOC2BL

Description (Vector)

There are at least two protein isoforms of the Double C2 protein, namely alpha (DOC2A) and beta (DOC2B), which contain two C2-like domains. DOC2A and DOC2B are encoded by different genes; these genes are at times confused with the unrelated DAB2 gene which was initially named DOC-2. DOC2B is expressed ubiquitously and is suggested to be involved in Ca(2+)-dependent intracellular vesicle trafficking in various types of cells.

Gene ID

8447

Gene Name (Vector)

double C2 domain beta

Gene Symbol

DOC2B

HGNC ID

HGNC:2986

ORF Size (aa)

1236

ORF Size (bp)

1236 bp

RefSeq ID

NM_003585

RefSeq Synonyms

NM_003585, BC153024, BC152720,

Species

human

UniGene ID

Hs.648240

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.