human DNM1L shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human DNM1L.
shADV-207202
Ad-h-DNM1L-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human DNM1L (dynamin 1 like). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
DLP1; DRP1; DVLP; DYMPLE; EMPF; EMPF1; HDYNIV
Description (Vector)
DNM1L is a member of the dynamin superfamily of GTPases. Members of the dynamin-related subfamily, including the S. cerevisiae proteins Dnm1 and Vps1, contain the N-terminal tripartite GTPase domain but do not have the pleckstrin homology or proline-rich domains. This protein establishes mitochondrial morphology through a role in distributing mitochondrial tubules throughout the cytoplasm. The gene has 3 alternatively spliced transcripts encoding different isoforms. These transcripts are alternatively polyadenylated.
Gene ID
10059
Gene Name (Vector)
dynamin 1 like
Gene Symbol
DNM1L
HGNC ID
HGNC:2973
ORF Size (aa)
2133
ORF Size (bp)
2133 bp
RefSeq ID
NM_012062
RefSeq Synonyms
NM_012063, NM_012062, NM_005690, NM_001330380, NM_001278466, NM_001278465, NM_001278464, NM_001278463, BC024590,
Species
human
UniGene ID
Hs.556296
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.