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human DCN shRNA silencing Adenovirus

Name 
Ad-h-DCN-shRNA
Cat No 
shADV-206662
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human DCN.

shADV-206662
Ad-h-DCN-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human DCN (decorin). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CSCD; DSPG2; PG40; PGII; PGS2; SLRR1B
Description (Vector)
DCN is a small cellular or pericellular matrix proteoglycan that is closely related in structure to biglycan protein. The encoded protein and biglycan are thought to be the result of a gene duplication. This protein is a component of connective tissue, binds to type I collagen fibrils, and plays a role in matrix assembly. It contains one attached glycosaminoglycan chain. This protein is capable of suppressing the growth of various tumor cell lines. There are multiple alternatively spliced transcript variants known for this gene. This gene is a candidate gene for Marfan syndrome.
Gene ID
1634
Gene Name (Vector)
decorin
Gene Symbol
DCN
HGNC ID
HGNC:2705
ORF Size (aa)
1080
ORF Size (bp)
1080 bp
RefSeq ID
NM_001920
RefSeq Synonyms
NM_133507, NM_133506, NM_133505, NM_133504, NM_133503, NM_001920, BC005322,
Species
human
UniGene ID
Hs.718429

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.