human CX3CR1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human CX3CR1.
shADV-206325
Ad-h-CX3CR1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human CX3CR1 (C-X3-C motif chemokine receptor 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
beta chemokine receptor-like 1;CCRL1;chemokine (C-C) receptor-like 1;chemokine (C-X3-C motif) receptor 1;chemokine (C-X3-C) receptor 1;CMKBRL1;CMK-BRL1;CMK-BRL-1;CMKDR1;CX3C chemokine receptor 1;C-X3-C CKR-1;CX3CR1;fractalkine receptor;GPR13;G-protein coupled receptor 13;GPRV28;V28
Description (eCommerce)
CX3CR1 is a receptor for the C-X3-C chemokine fractalkine (CX3CL1) which is present on many early leukocyte cells. Fractalkine is a transmembrane protein and chemokine involved in the adhesion and migration of leukocytes. CX3CR1-CX3CL1 signaling exerts distinct functions in different tissue compartments, such as immune response, inflammation, cell adhesion and chemotaxis. CX3CR1 is also a coreceptor for HIV-1, and some variations in this gene lead to increased susceptibility to HIV-1 infection and rapid progression to AIDS. [taken from NCBI Entrez Gene (Gene ID: 1524)].
Description (Vector)
Fractalkine is a transmembrane protein and chemokine involved in the adhesion and migration of leukocytes. The protein encoded by this gene is a receptor for fractalkine. The encoded protein also is a coreceptor for HIV-1, and some variations in this gene lead to increased susceptibility to HIV-1 infection and rapid progression to AIDS. Four transcript variants encoding two different isoforms have been found for this gene.
Gene ID
1524
Gene Name (eCommerce)
C-X3-C motif chemokine receptor 1
Gene Name (Vector)
C-X3-C motif chemokine receptor 1
Gene Symbol
CX3CR1
HGNC ID
HGNC:2558
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1068
ORF Size (bp)
1068 bp
Protein Name (eCommerce)
CX3C chemokine receptor 1
RefSeq ID
NM_001337
RefSeq Synonyms
NM_001337, NM_001171174, NM_001171172, NM_001171171, BC028078,
Research Areas (Faceted)
cancer,developmental_biology,cell_biology,signal_transduction,infectious_disease,immunology,neurobiology
Species
human
UniGene ID
Hs.78913
UniProt ID (eCommerce)
P49238
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.