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human CRHR2 shRNA silencing Adenovirus

Name 
Ad-h-CRHR2-shRNA
Cat No 
shADV-205998
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human CRHR2.

shADV-205998
Ad-h-CRHR2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human CRHR2 (corticotropin releasing hormone receptor 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CRF-RB; CRF2; CRFR2; HM-CRF
Description (Vector)
CRHR2 belongs to the G-protein coupled receptor 2 family, and the subfamily of corticotropin releasing hormone receptor. This receptor shows high affinity for corticotropin releasing hormone (CRH), and also binds CRH-related peptides such as urocortin. CRH is synthesized in the hypothalamus, and plays an important role in coordinating the endocrine, autonomic, and behavioral responses to stress and immune challenge. Studies in mice suggest that this receptor maybe involved in mediating cardiovascular homeostasis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Gene ID
1395
Gene Name (Vector)
corticotropin releasing hormone receptor 2
Gene Symbol
CRHR2
HGNC ID
HGNC:2358
ORF Size (aa)
1236
ORF Size (bp)
1236 bp
RefSeq ID
NM_001883
RefSeq Synonyms
NM_001883, NM_001202483, NM_001202482, NM_001202481, NM_001202475, BC096830,
Species
human
UniGene ID
Hs.546246

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.