human CRHR2 shRNA silencing AAV

Name
AAV-h-CRHR2-shRNA

Cat No
shAAV-205998

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human CRHR2.

shAAV-205998

AAV-h-CRHR2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CRHR2 (corticotropin releasing hormone receptor 2). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

CRF-RB; CRF2; CRFR2; HM-CRF

Description (Vector)

CRHR2 belongs to the G-protein coupled receptor 2 family, and the subfamily of corticotropin releasing hormone receptor. This receptor shows high affinity for corticotropin releasing hormone (CRH), and also binds CRH-related peptides such as urocortin. CRH is synthesized in the hypothalamus, and plays an important role in coordinating the endocrine, autonomic, and behavioral responses to stress and immune challenge. Studies in mice suggest that this receptor maybe involved in mediating cardiovascular homeostasis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Gene ID

1395

Gene Name (Vector)

corticotropin releasing hormone receptor 2

Gene Symbol

CRHR2

HGNC ID

HGNC:2358

ORF Size (aa)

1236

ORF Size (bp)

1236 bp

RefSeq ID

NM_001883

RefSeq Synonyms

NM_001883, NM_001202483, NM_001202482, NM_001202481, NM_001202475, BC096830,

Species

human

UniGene ID

Hs.546246

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.