human KLF10 Over-expression AAV

Name 
AAV-h-KLF10
Cat No 
AAV-213173
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human KLF10.

AAV-213173
AAV-h-KLF10

Ready-to-use AAV expressing Human KLF10 (Kruppel like factor 10). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
early growth response-alpha; EGRA; EGR-alpha; Krueppel-like factor 10; TGFB-inducible early growth response protein 1; TIEG; TIEG1; TIEG-1; transforming growth factor-beta-inducible early growth response protein 1; zinc finger transcription factor TIEG
Description (eCommerce)
Transforming growth factor-beta inducible early gene 1 (TIEG1) is a member of the 3 zinc-finger family of Kruppel-like transcription factors. It is also known as Kruppel-like factor 10 (KLF10). TIEG1 functions as an inducer or repressor of gene transcription to regulate the actions of estrogen and TGFbeta signaling and influences the processes of proliferation, differentiation, and apoptosis.
Gene ID
7071
Gene Name (eCommerce)
Kruppel like factor 10
Gene Name (Vector)
Kruppel like factor 10
Gene Symbol
KLF10
HGNC ID
HGNC:11810
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1443
ORF Size (bp)
1443 bp
Protein Name (eCommerce)
Krueppel-like factor 10
RefSeq ID
NM_005655
RefSeq Synonyms
NM_005655, NM_001032282, BC095399, BC011538,
Research Areas
Apoptosis,Signal Transduction,TGF-beta Signaling,Transcription Factor/Regulator,Zinc-finger
Research Areas (Faceted)
cell_biology,immunology,signal_transduction,transcription_translation
Species
human
Target Sentence
Transforming growth factor-beta inducible early gene 1 (TIEG1) is a member of the 3 zinc-finger family of Kruppel-like transcription factors. It is also known as Kruppel-like factor 10 (KLF10). TIEG1 functions as an inducer or repressor of gene transcription to regulate the actions of estrogen and TGFbeta signaling and influences the processes of proliferation, differentiation, and apoptosis.
UniGene ID
Hs.435001
UniProt ID (eCommerce)
Q13118

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.