human CD79A shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human CD79A.
shADV-204682
Ad-h-CD79A-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human CD79A (CD79a molecule). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
B-cell antigen receptor complex-associated protein alpha chain; CD antigen CD79a; CD79a antigen (immunoglobulin-associated alpha); CD79a molecule, immunoglobulin-associated alpha; IGA; ig-alpha; MB-1; MB-1 membrane glycoprotein; membrane-bound immunoglobulin-associated protein; surface IgM-associated protein
Description (eCommerce)
CD79A is required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. CD79A is also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P11912].
Description (Vector)
The B lymphocyte antigen receptor is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). Surface Ig non-covalently associates with two other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. This gene encodes the Ig-alpha protein of the B-cell antigen component. Alternatively spliced transcript variants encoding different isoforms have been described.
Gene ID
973
Gene Name (eCommerce)
CD79a molecule
Gene Name (Vector)
CD79a molecule
Gene Symbol
CD79A
HGNC ID
HGNC:1698
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
681
Protein Name (eCommerce)
B-cell antigen receptor complex-associated protein alpha chain
RefSeq ID
NM_001783
RefSeq Synonyms
NM_021601, NM_001783, BC113733, BC113731,
Research Areas
B-cell Receptor Signaling,Immunology,Signal Transduction
Research Areas (Faceted)
signal_transduction,immunology
Species
human
Target Sentence
CD79A is required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. CD79A is also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P11912].
UniGene ID
Hs.631567
UniProt ID (eCommerce)
P11912
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.