human CCR3 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human CCR3.
shADV-204536
Ad-h-CCR3-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human CCR3 (C-C motif chemokine receptor 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CC-CKR-3; CD193; CKR3; CMKBR3
Description (Vector)
CCR3 is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21. Alternatively spliced transcript variants have been described.
Gene ID
1232
Gene Name (Vector)
C-C motif chemokine receptor 3
Gene Symbol
CCR3
HGNC ID
HGNC:1604
ORF Size (aa)
1068
ORF Size (bp)
1068 bp
RefSeq ID
NM_001837
RefSeq Synonyms
NM_178329, NM_178328, NM_001837, NM_001164680, BC130320, BC130318, BC110297,
Species
human
UniGene ID
Hs.506190
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.