human KIAA1949 Over-expression AAV

Name 
AAV-h-KIAA1949
Cat No 
AAV-213053
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human PPP1R18.

AAV-213053
AAV-h-KIAA1949

Ready-to-use AAV expressing Human PPP1R18 (protein phosphatase 1 regulatory subunit 18). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
HKMT1098; KIAA1949; phostensin; protein phosphatase 1 F-actin cytoskeleton targeting subunit; Protein phosphatase 1 F-actin cytoskeleton-targeting subunit; Protein phosphatase 1 regulatory subunit 18
Description (eCommerce)
PPP1R18 may target protein phosphatase 1 to F-actin cytoskeleton [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q6NYC8].
Description (Vector)
Protein phosphatase-1 (PP1; see MIM 176875) interacts with regulatory subunits that target the enzyme to different cellular locations and change its activity toward specific substrates. Phostensin is a regulatory subunit that targets PP1 to F-actin (see MIM 102610) cytoskeleton (Kao et al., 2007 (PubMed 17374523)).(supplied by OMIM, Mar 2008)
Gene ID
170954
Gene Name (eCommerce)
protein phosphatase 1 regulatory subunit 18
Gene Name (Vector)
protein phosphatase 1 regulatory subunit 18
Gene Symbol
PPP1R18
HGNC ID
HGNC:29413
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1842
ORF Size (bp)
1842 bp
Protein Name (eCommerce)
Phostensin
RefSeq ID
NM_001134870
RefSeq Synonyms
NM_133471, NM_001134870, BC066644,
Research Areas
Cytoskeleton,Kinase/Phosphatase
Research Areas (Faceted)
cell_biology,signal_transduction
Species
human
Target Sentence
PPP1R18 may target protein phosphatase 1 to F-actin cytoskeleton [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q6NYC8].
UniGene ID
Hs.696054
UniProt ID (eCommerce)
Q6NYC8

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.