human CAMLG shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human CAMLG.
shADV-204011
Ad-h-CAMLG-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human CAMLG (calcium modulating ligand). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CAML; GET2
Description (Vector)
The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. The protein encoded by this gene functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin.
Gene ID
819
Gene Name (Vector)
calcium modulating ligand
Gene Symbol
CAMLG
HGNC ID
HGNC:1471
ORF Size (aa)
891
RefSeq ID
NM_001745
RefSeq Synonyms
NM_001745, BC130325,
Species
human
UniGene ID
Hs.529846
Recently Viewed Products
Ad-CMV-Luc
Cat No: 1000
Ad-CMV-Akt1 (Myr)
Cat No: 1020
Ad-CMV-Akt1 (dn)
Cat No: 1021
Ad-CMV-Akt1 (wt)
Cat No: 1022
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.