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human CABIN1 shRNA silencing Adenovirus

Name 
Ad-h-CABIN1-shRNA
Cat No 
shADV-203891
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human CABIN1.

shADV-203891
Ad-h-CABIN1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human CABIN1 (calcineurin binding protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CAIN; KB-318B8.7; PPP3IN
Description (Vector)
Calcineurin plays an important role in the T-cell receptor-mediated signal transduction pathway. The protein encoded by this gene binds specifically to the activated form of calcineurin and inhibits calcineurin-mediated signal transduction. The encoded protein is found in the nucleus and contains a leucine zipper domain as well as several PEST motifs, sequences which confer targeted degradation to those proteins which contain them. Alternative splicing results in multiple transcript variants encoding two different isoforms.
Gene ID
23523
Gene Name (Vector)
calcineurin binding protein 1
Gene Symbol
CABIN1
HGNC ID
HGNC:24187
ORF Size (aa)
6426
ORF Size (bp)
6426 bp
RefSeq ID
NM_012295
RefSeq Synonyms
NM_012295, NM_001201429, NM_001199281, BC054497,
Species
human
UniGene ID
Hs.517478

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.