human C1QBP shRNA silencing Adenovirus

Name 
Ad-h-C1QBP-shRNA
Cat No 
shADV-203134
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human C1QBP.

shADV-203134
Ad-h-C1QBP-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human C1QBP (complement C1q binding protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
ASF/SF2-associated protein p32; C1q globular domain-binding protein; C1qBP; complement component 1 Q subcomponent-binding protein, mitochondrial; complement component 1, q subcomponent binding protein; COXPD33; GC1QBP; gC1qR; gC1Q-R; gC1q-R protein; glycoprotein gC1qBP; HABP1; hyaluronan-binding protein 1; mitochondrial matrix protein p32; p32; p33; SF2AP32; SF2p32; splicing factor SF2-associated protein
Description (eCommerce)
C1qBP (complement component 1q subcomponent-binding protein) is known to bind to the globular heads of the human complement component, C1q, and inhibit C1 activation. This protein has also been identified as the p32 subunit of pre-mRNA splicing factor SF2, as well as a hyaluronic acid-binding protein (HABP1) [taken from NCBI Entrez Gene (Gene ID: 10084)].
Description (Vector)
The human complement subcomponent C1q associates with C1r and C1s in order to yield the first component of the serum complement system. The protein encoded by this gene is known to bind to the globular heads of C1q molecules and inhibit C1 activation. This protein has also been identified as the p32 subunit of pre-mRNA splicing factor SF2, as well as a hyaluronic acid-binding protein.
Gene ID
708
Gene Name (eCommerce)
complement C1q binding protein
Gene Name (Vector)
complement C1q binding protein
Gene Symbol
C1QBP
HGNC ID
HGNC:1243
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
849
Protein Name (eCommerce)
Complement component 1 Q subcomponent-binding protein, mitochondrial
RefSeq ID
NM_001212
RefSeq Synonyms
NM_001212, BC013731, BC000435,
Research Areas
Apoptosis,Host-Virus Interactions,Immunology,Innate Immunity,Mitochondrion,mRNA Processing,mRNA Splicing,RNA Processing,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,genetics,immunology,infectious_disease,transcription_translation
Species
human
Target Sentence
C1qBP (complement component 1q subcomponent-binding protein) is known to bind to the globular heads of the human complement component, C1q, and inhibit C1 activation. This protein has also been identified as the p32 subunit of pre-mRNA splicing factor SF2, as well as a hyaluronic acid-binding protein (HABP1) [taken from NCBI Entrez Gene (Gene ID: 10084)].
UniGene ID
Hs.555866
UniProt ID (eCommerce)
Q07021

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.