human C1QB shRNA silencing Adenovirus

Name
Ad-h-C1QB-shRNA

Cat No
shADV-203133

Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human C1QB.

shADV-203133

Ad-h-C1QB-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human C1QB (complement C1q B chain). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Validated

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Description (Vector)

C1QB encodes a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N terminus and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1. C1QB encodes the B-chain polypeptide of human complement subcomponent C1q

Gene ID

713

Gene Name (Vector)

complement C1q B chain

Gene Symbol

C1QB

HGNC ID

HGNC:1242

ORF Size (aa)

762

ORF Size (bp)

762 bp

RefSeq ID

NM_000491

RefSeq Synonyms

NM_000491, BC008983,

Species

human

UniGene ID

Hs.8986

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.