human C10ORF54 shRNA silencing Adenovirus

Name 
Ad-h-C10ORF54-shRNA
Cat No 
shADV-202428
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human VSIR.

shADV-202428
Ad-h-C10ORF54-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human VSIR (V-set immunoregulatory receptor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
B7H5; B7-H5; C10orf54; DD1alpha; Death Domain1alpha; GI24; PD-1H; PDCD1 homolog; platelet receptor GI24; PP2135; SISP1; sisp-1; stress-induced secreted protein-1; V-domain Ig suppressor of T cell activation; VISTA; V-set domain-containing immunoregulatory receptor; V-set immunoregulatory receptor; V-type immunoglobulin domain-containing suppressor of T-cell activation
Description (eCommerce)
VISTA is an immunoregulatory receptor which inhibits the T-cell response (PubMed:24691993). It may promote differentiation of embryonic stem cells, by inhibiting BMP4 signaling (By similarity). VISTA may stimulate MMP14-mediated MMP2 activation [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9H7M9].
Gene ID
64115
Gene Name (eCommerce)
V-set immunoregulatory receptor
Gene Name (Vector)
V-set immunoregulatory receptor
Gene Symbol
VSIR
HGNC ID
HGNC:30085
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
936
ORF Size (bp)
936 bp
Protein Name (eCommerce)
V-type immunoglobulin domain-containing suppressor of T-cell activation
RefSeq ID
NM_022153
RefSeq Synonyms
NM_022153, BC020568,
Research Areas
Cell Biology,Immunology,Signal Transduction,Transport
Research Areas (Faceted)
signal_transduction,cell_biology,immunology,cell_biology
Species
human
Target Sentence
VISTA is an immunoregulatory receptor which inhibits the T-cell response (PubMed:24691993). It may promote differentiation of embryonic stem cells, by inhibiting BMP4 signaling (By similarity). VISTA may stimulate MMP14-mediated MMP2 activation [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9H7M9].
UniGene ID
Hs.47382
UniProt ID (eCommerce)
Q9H7M9

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.