human BMP4 shRNA silencing Adenovirus

Name 
Ad-h-BMP4-shRNA
Cat No 
shADV-202197
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human BMP4.

shADV-202197
Ad-h-BMP4-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human BMP4 (bone morphogenetic protein 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
BMP2B; BMP2B1; MCOPS6; OFC11; ZYME
Description (Vector)
BMP4 is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. This particular family member plays an important role in the onset of endochondral bone formation in humans, and a reduction in expression has been associated with a variety of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Alternative splicing in the 5' untranslated region of this gene has been described and three variants are described, all encoding an identical protein.
Gene ID
652
Gene Name (Vector)
bone morphogenetic protein 4
Gene Symbol
BMP4
HGNC ID
HGNC:1071
ORF Size (aa)
1227
ORF Size (bp)
1227 bp
RefSeq ID
NM_001202
RefSeq Synonyms
NM_130851, NM_130850, NM_001202, BC020546,
Species
human
UniGene ID
Hs.68879

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.