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human BEX2 shRNA silencing Adenovirus

Name 
Ad-h-BEX2-shRNA
Cat No 
shADV-202110
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human BEX2.

shADV-202110
Ad-h-BEX2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human BEX2 (brain expressed X-linked 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
BEX1; DJ79P11.1
Description (Vector)
BEX2 belongs to the brain expressed X-linked gene family. The encoded protein interacts with the transcription factor LIM domain only 2 in a DNA-binding complex that recognizes the E-box element and promotes transcription. BEX2 has been found to be a tumor suppressor that is silenced in human glioma. In breast cancer cells, this gene product modulates apoptosis in response to estrogen and tamoxifen, and enhances the anti-proliferative effect of tamoxifen. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene ID
84707
Gene Name (Vector)
brain expressed X-linked 2
Gene Symbol
BEX2
HGNC ID
HGNC:30933
ORF Size (aa)
387
ORF Size (bp)
387 bp
RefSeq ID
NM_032621
RefSeq Synonyms
NM_032621, NM_001168401, NM_001168400, NM_001168399, BC015522,
Species
human
UniGene ID
Hs.398989

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.