human BANF1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human BANF1.
shADV-201956
Ad-h-BANF1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human BANF1 (barrier to autointegration factor 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
BAF; BCRP1; D14S1460; NGPS
Description (Vector)
BANF1 was first identified by its ability to protect retroviruses from intramolecular integration and therefore promote intermolecular integration into the host cell genome. The protein forms a homodimer which localizes to both the nucleus and cytoplasm and is specifically associated with chromosomes during mitosis. This protein binds to double stranded DNA in a non-specific manner and also binds to LEM-domain containing proteins of the nuclear envelope. This protein is thought to facilitate nuclear reassembly by binding with both DNA and inner nuclear membrane proteins and thereby recruit chromatin to the nuclear periphery. Alternative splicing results in multiple transcript variants encoding the same protein.
Gene ID
8815
Gene Name (Vector)
barrier to autointegration factor 1
Gene Symbol
BANF1
HGNC ID
HGNC:17397
ORF Size (aa)
270
ORF Size (bp)
270 bp
RefSeq ID
NM_003860
RefSeq Synonyms
NM_003860, NM_001143985, BC107702, BC005942,
Species
human
UniGene ID
Hs.433759
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.