human ATP6V1C2 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human ATP6V1C2.
shADV-201761
Ad-h-ATP6V1C2-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human ATP6V1C2 (ATPase H+ transporting V1 subunit C2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ATP6C2; VMA5
Description (Vector)
ATP6V1C2 encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A,three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. ATP6V1C2 encodes alternate transcriptional splice variants, encoding different V1 domain C subunit isoforms.
Gene ID
245973
Gene Name (Vector)
ATPase H+ transporting V1 subunit C2
Gene Symbol
ATP6V1C2
HGNC ID
HGNC:18264
ORF Size (aa)
1146
ORF Size (bp)
1146 bp
RefSeq ID
NM_144583
RefSeq Synonyms
NM_144583, NM_001039362, BC012142,
Species
human
UniGene ID
Hs.580464
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.