human C4BPB Adenovirus
This is an Adenovirus expressing Human C4BPB.
ADV-203441
Ad-h-C4BPB
Ready-to-use Adenovirus expressing Human C4BPB (complement component 4 binding protein beta). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
C4BP
Description (Vector)
C4BPB encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. A single, unique beta-chain encoded by this gene assembles with seven identical alpha-chains into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. C4b-binding protein has a regulatory role in the coagulation system also, mediated through the beta-chain binding of protein S, a vitamin K-dependent protein that serves as a cofactor of activated protein C. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Alternative splicing gives rise to multiple transcript variants.
Gene ID
725
Gene Name (Vector)
complement component 4 binding protein beta
Gene Symbol
C4BPB
HGNC ID
HGNC:1328
ORF Size (aa)
756
ORF Size (bp)
756 bp
RefSeq ID
NM_000716
RefSeq Synonyms
NM_001017367, NM_001017366, NM_001017365, NM_001017364, NM_000716, BC005378,
Species
human
UniGene ID
Hs.99886
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.