human ARNTL shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human ARNTL.
shADV-201453
Ad-h-ARNTL-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human ARNTL (aryl hydrocarbon receptor nuclear translocator like). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ARNT-like protein 1, brain and muscle; aryl hydrocarbon receptor nuclear translocator-like protein 1; basic helix-loop-helix family member e5; basic-helix-loop-helix-PAS orphan MOP3; basic-helix-loop-helix-PAS protein MOP3; bHLHe5; bHLH-PAS protein JAP3; BMAL1; BMAL1c; brain and muscle ARNT-like 1; class E basic helix-loop-helix protein 5; JAP3; member of PAS protein 3; member of PAS superfamily 3; MOP3; PAS domain containing 3; PAS domain-containing protein 3; PASD3; testis tissue sperm-binding protein Li 50e; TIC
Description (eCommerce)
BMAL1 [brain and muscle aryl hydrocarbon receptor nuclear translocator (ARNT)-like 1] is a basic helix-loop-helix protein that forms a heterodimer with CLOCK. This complex binds an E-box upstream of the PER1 gene, activating this gene and possibly other circadian rhythym-associated genes [taken from NCBI Entrez Gene (GeneID: 406)].
Description (Vector)
ARNTL is a basic helix-loop-helix protein that forms a heterodimer with CLOCK. This complex binds an E-box upstream of the PER1 gene, activating this gene and possibly other circadian rhythym-associated genes. Three transcript variants encoding two different isoforms have been found for this gene.
Gene ID
406
Gene Name (eCommerce)
aryl hydrocarbon receptor nuclear translocator like
Gene Name (Vector)
aryl hydrocarbon receptor nuclear translocator like
Gene Symbol
ARNTL
HGNC ID
HGNC:701
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1878
ORF Size (bp)
1878 bp
Protein Name (eCommerce)
Aryl hydrocarbon receptor nuclear translocator-like protein 1
RefSeq ID
NM_001178
RefSeq Synonyms
NM_001297724, NM_001297722, NM_001297719, NM_001178, NM_001030273, NM_001030272, BC041129, BC031214, BC016674,
Research Areas
Aging,Hedgehog Signaling,Host-Virus Interactions,Metabolism/Metabolic Process,Neurobiology,RNA Binding,Signal Transduction,Transcription Factor/Regulator,Transport
Research Areas (Faceted)
cell_biology,infectious_disease,metabolism,neurobiology,signal_transduction,transcription_translation
Species
human
Target Sentence
BMAL1 [brain and muscle aryl hydrocarbon receptor nuclear translocator (ARNT)-like 1] is a basic helix-loop-helix protein that forms a heterodimer with CLOCK. This complex binds an E-box upstream of the PER1 gene, activating this gene and possibly other circadian rhythym-associated genes [taken from NCBI Entrez Gene (GeneID: 406)].
UniGene ID
Hs.65734
UniProt ID (eCommerce)
O00327
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.