human ARHGEF16 shRNA silencing Adenovirus

Name 
Ad-h-ARHGEF16-shRNA
Cat No 
shADV-201359
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human ARHGEF16.

shADV-201359
Ad-h-ARHGEF16-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human ARHGEF16 (Rho guanine nucleotide exchange factor 16). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
60
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
ephexin4; ephexin-4; GEF16; NBR; Rho guanine exchange factor (GEF) 16; Rho guanine nucleotide exchange factor (GEF) 16; rho guanine nucleotide exchange factor 16
Description (eCommerce)
The gene for ARHGEF16 [Rho guanine exchange factor (GEF)16] was isolated as a candidate gene for human neuroblastoma. It is a member of the Rho/Rac GEF family of proteins which catalyze the exchange of GDP for GTP on the GTPases, Rho and Rac, to activate downstream signaling pathways.
Description (Vector)
Although the specific function of this protein is not known yet, it is thought to be involved in protein-protein and protein-lipid interactions.
Gene ID
27237
Gene Name (eCommerce)
Rho guanine nucleotide exchange factor 16
Gene Name (Vector)
Rho guanine nucleotide exchange factor 16
Gene Symbol
ARHGEF16
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1266
ORF Size (bp)
1266 bp
Protein Name (eCommerce)
Rho guanine nucleotide exchange factor 16
RefSeq ID
NM_014448
RefSeq Synonyms
NM_014448, BC051838, BC002681,
Research Areas
Apoptosis,GPCR Signaling,Neurobiology,NGF Signaling,Signal Transduction
Research Areas (Faceted)
cell_biology,neurobiology,signal_transduction
Species
human
Target Sentence
The gene for ARHGEF16 [Rho guanine exchange factor (GEF)16] was isolated as a candidate gene for human neuroblastoma. It is a member of the Rho/Rac GEF family of proteins which catalyze the exchange of GDP for GTP on the GTPases, Rho and Rac, to activate downstream signaling pathways.
UniGene ID
Hs.87435
UniProt ID (eCommerce)
Q5VV41

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.