human KCNJ1 Over-expression AAV
This is an AAV expressing Human KCNJ1.
AAV-212708
AAV-h-KCNJ1
Ready-to-use AAV expressing Human KCNJ1 (potassium voltage-gated channel subfamily J member 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
KIR1.1; ROMK; ROMK1
Description (Vector)
Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. It is activated by internal ATP and probably plays an important role in potassium homeostasis. The encoded protein has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Mutations in this gene have been associated with antenatal Bartter syndrome, which is characterized by salt wasting, hypokalemic alkalosis, hypercalciuria, and low blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene ID
3758
Gene Name (Vector)
potassium voltage-gated channel subfamily J member 1
Gene Symbol
KCNJ1
HGNC ID
HGNC:6255
ORF Size (aa)
1176
ORF Size (bp)
1176 bp
RefSeq ID
NM_153764
RefSeq Synonyms
NM_153767, NM_153766, NM_153765, NM_153764, NM_000220, BC136361, BC136360, BC074752,
Species
human
UniGene ID
Hs.527830
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.