human AKR1C4 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human AKR1C4.
shADV-200688
Ad-h-AKR1C4-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human AKR1C4 (aldo-keto reductase family 1 member C4). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
3-alpha-HSD; C11; CDR; CHDR; DD-4; DD4; HAKRA
Description (Vector)
AKR1C4 encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. AKR1C4 shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.
Gene ID
1109
Gene Name (Vector)
aldo-keto reductase family 1 member C4
Gene Symbol
AKR1C4
HGNC ID
HGNC:387
ORF Size (aa)
972
ORF Size (bp)
972 bp
RefSeq ID
NM_001818
RefSeq Synonyms
NM_001818, BC020744,
Species
human
UniGene ID
Hs.567245
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.