human AKAP3 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human AKAP3.
shADV-200657
Ad-h-AKAP3-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human AKAP3 (A-kinase anchoring protein 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AKAP 110; AKAP110; CT82; FSP95; HEL159; PRKA3; SOB1
Description (Vector)
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family, and is expressed in testis only. The encoded protein contains an RII-binding domain, and is predicted to participate in protein-protein interactions with the R-subunit of the PKA. This protein is localized to the ribs of the fibrous sheath in the principal piece of the sperm tail. It may function as a regulator of both motility- and head-associated functions such as capacitation and the acrosome reaction.
Gene ID
10566
Gene Name (Vector)
A-kinase anchoring protein 3
Gene Symbol
AKAP3
HGNC ID
HGNC:373
ORF Size (aa)
2562
ORF Size (bp)
2562 bp
RefSeq ID
NM_006422
RefSeq Synonyms
NM_006422, NM_001278309, BC047535,
Species
human
UniGene ID
Hs.98397
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.